Chapter 492 Unbelievable
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Yi Hu Zhuo Jiu Yi Sui Feng
Chapter 492 Unbelievable
"Then, I don't know Professor Lu, is there anything we can help with?"
Hearing this, Director Bi straightened his expression, looked at Lu Lin, and said very formally.
"I really need your help with something. I'm developing a drug that can treat cancer, but it needs clinical trials. That's why I asked Minister Qin to help me find candidates."
Hearing that Lu Lin was going to get involved in the medical field, Director Bi and Zheng Xin were stunned. They looked at Lu Lin, not knowing what to say.
"Professor Lu, I know that your achievements in other fields are of trans-epochal significance."
"However, the medical field is of great importance. It's not that I don't trust you, it's just."
Medical care is a major issue in people's livelihood, and the supervision is naturally very strict.
The normal development of a drug, from project approval, to development, development, preclinical experiments, phase one, two, and three clinical trials, is a very long process. Even in an emergency, it will take a year or two to get the green light all the way. It's time.
Moreover, Lu Lin has never been involved in the medical field before, so Director Bi and Zheng Xin are also somewhat difficult to do.
"Both of you, it's all right, Professor Lu, take out the materials."
"it is good."
Later, Lu Lin also took out a document, which recorded the data of animal experiments when he and Yan Ruowei were developing drugs.
After receiving the experimental data from Lu Lin and taking a look at it, the expressions of Director Bi and Zheng Xin changed drastically.
"This, is this true?!"
"The mice whose cancer cells have metastasized can't detect the cancer cells after eight hours?!"
The experimental data given by Lu Lin really surprised the two of them.
After all, such a curative cancer drug is basically impossible for the two of them.
"Professor Lu, are you kidding me?!"
After seeing the results of the experiment, Director Bi and Zheng Xin's first reaction must have been disbelief. If it wasn't Lu Lin who was standing in front of them at this time, they would have slammed the door and left long ago.
"I'm not kidding, it's true, it's just that this healing method is a special method that can be used for emergency patients."
"But, this kind of treatment is relatively expensive."
"So it is not suitable for civilian use for the time being."
Hearing this, Zheng Xin and Director Bi also had natural expressions on their faces.
"However, Professor Lu, I'm quite curious about your special method, what kind of method is it?"
"Even if the cost is high, some wealthy patients should still be able to afford it."
"No, this thing, at present, is not only expensive, but also top-secret."
"It cannot be used casually on ordinary people."
Hearing this, Director Bi and Zheng Xin's expressions also changed, they hurriedly closed the file, looked at Lu Lin, and said.
"Professor Lu, aren't you harming us both?"
"This level of information, we may have a big problem after reading it."
Seeing the reaction of the two, Lu Lin also smiled and comforted.
"Don't worry, I let you see that no one will come to trouble you."
In fact, the information that Lu Lin showed the two of them was the therapeutic effect of the medicine modified by using regenerative medicine.
This medicine, because of the repairing effect of the regenerative medicine, can clear the abnormal cells in the body of the injected person, thereby achieving the effect of clearing the cancer cells.
However, using regenerative potions for this is really a bit too overkill.
So what Lu Lin thought was that it would be better to develop a drug for the treatment of cancer with a slightly lower cost and suitable for the public.
Otherwise, if the price is too expensive, most people can't afford it.
"Then, Professor Lu showed us this?"
"Oh, please provide some research direction."
"To treat cancer, the first step must be to destroy cancer cells first."
"However, the division speed of cancer cells is too fast, and it basically feels like a wild fire that can't be burned out, and the spring breeze blows and regenerates."
"Although many patients obviously have no cancer cells detected when they are discharged from the hospital, they may relapse after a few years. This is because once cancer cells are produced, in fact, changes have taken place at the level of cell genes. .”
"And this part of the abnormal cells that have mutated cannot be eliminated by chemotherapy or the like. This is the reason why many cancer patients relapse."
"To treat cancer, the first step is to eliminate the diseased cells, and the second step is to repair the diseased genes."
"Actually, the first step is relatively simple. I already have an idea for this, but the second step involves genetic medicine. This involves the things in the information I just showed you. It is still top secret, and The cost is high and it is not suitable for popular civilian use."
"However, even if it is the first step, it is not that simple. I don't have so many cancer cell samples in my hand, and my laboratory does not have the corresponding research and development conditions, so I came to the Ministry of Health. I want to cooperate with you to develop this drug."
Hearing this, Director Bi and Zheng Xin also nodded, and even Minister Qin who was beside him also spoke.
"Professor Lu needs us to provide any conditions, you can just say it."
"The laboratory. Because my idea requires traditional small molecules and biological macromolecules. Therefore, in terms of laboratories, chemical medicine laboratories and biological laboratories may be required. Biological laboratories, preferably P4 laboratories, The safety level is higher, and the types of samples are more complete, which may be more helpful for research and development."
Lu Lin thought for a while and said.
"Small molecules conjugated to biomacromolecules? ADC drugs?" Director Bi asked Lu Lin.
"It can be regarded as a conjugated ADC drug. However, because the drug has multiple escape mechanisms, it is difficult to use a single drug. Compared with other drugs, the possible concatemers I want to make are similar to a drug army. The diseased area is blocked globally, and then the associated drug is used to target the tumor cells. After hitting the target, the protease abnormally expressed on the surface of the tumor is used to dissolve the small molecule linkages, and the small molecule enters the tumor cells and kills the tumor cells! At the same time, because Block off the area, release special signals, reactivate the autoimmune system, and use T cells and phagocytes to chase and intercept the escaping tumor cells, so as to ensure that the drug can completely kill the tumor, prolong the patient's living condition, improve the quality of life, and lay a foundation for subsequent gene repair of mutations. , completely eradicate cancer cell recurrence, and provide time."
Hearing Lu Lin's words, Director Bi and Zheng Xin felt a little... unrealistic.
Because ADC is a therapy that has just emerged in recent years. Even the conjugated drugs of biological macromolecules and small molecules still have many problems, let alone multi-drugs?
Seeing the suspicion in the eyes of Director Bi and Zheng Xin, Minister Qin said with a smile: "You two, don't you think it's a little weird?"
(End of this chapter)
"Then, I don't know Professor Lu, is there anything we can help with?"
Hearing this, Director Bi straightened his expression, looked at Lu Lin, and said very formally.
"I really need your help with something. I'm developing a drug that can treat cancer, but it needs clinical trials. That's why I asked Minister Qin to help me find candidates."
Hearing that Lu Lin was going to get involved in the medical field, Director Bi and Zheng Xin were stunned. They looked at Lu Lin, not knowing what to say.
"Professor Lu, I know that your achievements in other fields are of trans-epochal significance."
"However, the medical field is of great importance. It's not that I don't trust you, it's just."
Medical care is a major issue in people's livelihood, and the supervision is naturally very strict.
The normal development of a drug, from project approval, to development, development, preclinical experiments, phase one, two, and three clinical trials, is a very long process. Even in an emergency, it will take a year or two to get the green light all the way. It's time.
Moreover, Lu Lin has never been involved in the medical field before, so Director Bi and Zheng Xin are also somewhat difficult to do.
"Both of you, it's all right, Professor Lu, take out the materials."
"it is good."
Later, Lu Lin also took out a document, which recorded the data of animal experiments when he and Yan Ruowei were developing drugs.
After receiving the experimental data from Lu Lin and taking a look at it, the expressions of Director Bi and Zheng Xin changed drastically.
"This, is this true?!"
"The mice whose cancer cells have metastasized can't detect the cancer cells after eight hours?!"
The experimental data given by Lu Lin really surprised the two of them.
After all, such a curative cancer drug is basically impossible for the two of them.
"Professor Lu, are you kidding me?!"
After seeing the results of the experiment, Director Bi and Zheng Xin's first reaction must have been disbelief. If it wasn't Lu Lin who was standing in front of them at this time, they would have slammed the door and left long ago.
"I'm not kidding, it's true, it's just that this healing method is a special method that can be used for emergency patients."
"But, this kind of treatment is relatively expensive."
"So it is not suitable for civilian use for the time being."
Hearing this, Zheng Xin and Director Bi also had natural expressions on their faces.
"However, Professor Lu, I'm quite curious about your special method, what kind of method is it?"
"Even if the cost is high, some wealthy patients should still be able to afford it."
"No, this thing, at present, is not only expensive, but also top-secret."
"It cannot be used casually on ordinary people."
Hearing this, Director Bi and Zheng Xin's expressions also changed, they hurriedly closed the file, looked at Lu Lin, and said.
"Professor Lu, aren't you harming us both?"
"This level of information, we may have a big problem after reading it."
Seeing the reaction of the two, Lu Lin also smiled and comforted.
"Don't worry, I let you see that no one will come to trouble you."
In fact, the information that Lu Lin showed the two of them was the therapeutic effect of the medicine modified by using regenerative medicine.
This medicine, because of the repairing effect of the regenerative medicine, can clear the abnormal cells in the body of the injected person, thereby achieving the effect of clearing the cancer cells.
However, using regenerative potions for this is really a bit too overkill.
So what Lu Lin thought was that it would be better to develop a drug for the treatment of cancer with a slightly lower cost and suitable for the public.
Otherwise, if the price is too expensive, most people can't afford it.
"Then, Professor Lu showed us this?"
"Oh, please provide some research direction."
"To treat cancer, the first step must be to destroy cancer cells first."
"However, the division speed of cancer cells is too fast, and it basically feels like a wild fire that can't be burned out, and the spring breeze blows and regenerates."
"Although many patients obviously have no cancer cells detected when they are discharged from the hospital, they may relapse after a few years. This is because once cancer cells are produced, in fact, changes have taken place at the level of cell genes. .”
"And this part of the abnormal cells that have mutated cannot be eliminated by chemotherapy or the like. This is the reason why many cancer patients relapse."
"To treat cancer, the first step is to eliminate the diseased cells, and the second step is to repair the diseased genes."
"Actually, the first step is relatively simple. I already have an idea for this, but the second step involves genetic medicine. This involves the things in the information I just showed you. It is still top secret, and The cost is high and it is not suitable for popular civilian use."
"However, even if it is the first step, it is not that simple. I don't have so many cancer cell samples in my hand, and my laboratory does not have the corresponding research and development conditions, so I came to the Ministry of Health. I want to cooperate with you to develop this drug."
Hearing this, Director Bi and Zheng Xin also nodded, and even Minister Qin who was beside him also spoke.
"Professor Lu needs us to provide any conditions, you can just say it."
"The laboratory. Because my idea requires traditional small molecules and biological macromolecules. Therefore, in terms of laboratories, chemical medicine laboratories and biological laboratories may be required. Biological laboratories, preferably P4 laboratories, The safety level is higher, and the types of samples are more complete, which may be more helpful for research and development."
Lu Lin thought for a while and said.
"Small molecules conjugated to biomacromolecules? ADC drugs?" Director Bi asked Lu Lin.
"It can be regarded as a conjugated ADC drug. However, because the drug has multiple escape mechanisms, it is difficult to use a single drug. Compared with other drugs, the possible concatemers I want to make are similar to a drug army. The diseased area is blocked globally, and then the associated drug is used to target the tumor cells. After hitting the target, the protease abnormally expressed on the surface of the tumor is used to dissolve the small molecule linkages, and the small molecule enters the tumor cells and kills the tumor cells! At the same time, because Block off the area, release special signals, reactivate the autoimmune system, and use T cells and phagocytes to chase and intercept the escaping tumor cells, so as to ensure that the drug can completely kill the tumor, prolong the patient's living condition, improve the quality of life, and lay a foundation for subsequent gene repair of mutations. , completely eradicate cancer cell recurrence, and provide time."
Hearing Lu Lin's words, Director Bi and Zheng Xin felt a little... unrealistic.
Because ADC is a therapy that has just emerged in recent years. Even the conjugated drugs of biological macromolecules and small molecules still have many problems, let alone multi-drugs?
Seeing the suspicion in the eyes of Director Bi and Zheng Xin, Minister Qin said with a smile: "You two, don't you think it's a little weird?"
(End of this chapter)
