Chapter 331: Mass production of papers! Additional findings from ward rounds!

Major hospitals have successively issued articles. According to the indications for use formulated by Xu Qiu in the popular science article, they have used naproxen therapy for some patients with clinical symptoms and unexplained fever, and have achieved quite significant results.

Not to mention Baiyun Province, at the request of the Health Commission and the health department, naproxen was included in the provincial medical insurance, the price was further reduced, and a large number of drugs were booked in advance.

Outside the province, many hospitals were surprised to find that the effect of this drug is far more than just fighting cancer fever.

It has a more obvious advantage in clinical practice.

That is, as a means of verification, to determine whether the patient has cancer fever, it can even detect some tumors that cannot be detected by imaging at an early stage...

For example, Tao Changhan.

His tumor index is very low, and clinically it is generally not considered to have cancer. Even if there is, it is an extremely early cancer that has no meaning for examination and treatment.

Doing CT, MRI, etc. is time-consuming, labor-intensive, and expensive.

However, if there is an unexplained fever, taking naproxen, the treatment is effective, then it is cancer fever, and early diagnosis of cancer, which is more reliable and convenient than other examination items.

For this reason, the demand for naproxen in many cancer hospitals and fever clinics suddenly increased.

The manufacturers did not realize this.

This also led to the sale of naproxen in pharmacies. Even in Baiyun Province, which had prepared for a rainy day and signed a purchase contract long ago, it was facing a situation of supply exceeding demand.

When the effect of naproxen received more positive feedback in the clinic, the Baiyun Provincial Health Commission, the Gynecological Tumor Prevention and Research Society, the Tumor Society, etc. jointly issued a document and formulated a new clinical guideline in the fastest time!

Standards for the use of naproxen for treatment:

1. The body temperature is higher than 37.8 degrees Celsius once a day

2. Fever lasts for more than two weeks (or repeated fever in critically ill patients)

3. Physical examination, body fluid culture and imaging did not indicate infection

4. Exclude drug allergy, transfusion reaction, chemotherapy reaction

5. Adequate antibiotic treatment for one week is ineffective; or other cooling measures are ineffective.

…

This new medication indication quickly entered the Baiyun Provincial Tumor Discipline Guidelines, and then affected several surrounding provinces.

Although other provinces did not follow up, the latest guidelines of Baiyun Province were already used in hospitals.

For a time, the sales of naproxen in China soared thousands of times.

"Conscience medicine" and "good medicine for the people" were given titles such as naproxen, and some people even called it a miracle drug.

The only regret is that although the domestic oncology discipline was stirred up by Xu Qiu's lecture and popular science, naproxen did not cause much waves abroad.

In other words, there was no news from foreign hospitals at all.

Once naproxen, which costs a few dollars, is really popularized, it will shake the interests of many pharmaceutical giants and will directly impact many drugs that use this as a selling point.

It can even affect the imaging department and the laboratory department.

After all, many patients with unexplained fever cannot be solved in the end, that is, they continue to do laboratory tests and imaging analysis. After the reputation of naproxen started from Linhai First Hospital, this cheap drug will replace various expensive tests and become the first choice.

…

In the past few days, Tao Changhan, as the first patient in the history of Linhai First Hospital to use naproxen to reduce fever and directly promoted the formulation of new drug indications and clinical guidelines, has received special care.

The doctors at Linhai First Hospital were almost grinning.

Many doctors were worried about not having cases and thesis directions.

Now they are suddenly enlightened.

In just a few weeks, a large number of related papers have begun to be studied.

"Application of Naproxen in the Differential Diagnosis of Cancer Fever";

"Application of Naproxen Test in the Differential Diagnosis of Cancer Fever and Infectious Fever of Lung Cancer";

"Observation of the Efficacy of Naproxen in the Treatment of Tumor Fever of Advanced Colorectal Cancer"...

This also made Tao Changhan's ward quite lively.

Tao Changhan's daughter almost grinned, and she never refused any doctor who came to ask about medical history and research data.

"If it were in the past, you female doctors would have been teased by my father several times, but unfortunately he has mutism now, so he can't enjoy it!" Tao joked.

On the hospital bed, Tao Changhan looked like he had lost all hope in life.

He was just taciturn, not deaf!

Can you please not say bad things about me in front of me?

"Doctor Xu!"

At this moment, the door of the ward was pushed open, and the female doctors in the ward immediately left Tao Changhan and greeted him with spring on their faces.

"Yeah."

Without raising his head, Xu Qiu glanced at Tao Changhan's examination report when he walked into the ward.

Various lists showed that there were no major problems and met the indications for discharge.

However, Xu Qiu was still not at ease, so before signing the discharge notice, he planned to come in person for the last full-body examination.

"Tao Changhan?"

Although he had long remembered the patient's appearance, Xu Qiu did not omit the necessary procedures.

"Check again before discharge, and follow up if there is no problem."

Tao Changhan opened his eyes a little, without making a sound, but his body still made a cooperative gesture.

Xu Qiu focused on the relevant examinations of the head, face, and nervous system.

There was no tenderness or mass in the head.

The cornea has no cloudiness or scars.

Pupil...

Xu Qiu was slightly stunned, and he found that something was wrong with the patient at a glance.

"Look up."

"Look down..."

After a few simple examinations, Xu Qiu wrote down two diagnoses on the examination form.

Both eyes cannot look up;

Mydriasis;

Eye movement disorder;

These are the most characteristic manifestations of nuclear injury.

The contralateral upward vision is limited because of the destruction of the superior rectus nucleus on the lesion side, or numbness of the oculomotor nerve.

The patient himself has no eye trauma and no underlying diseases related to the nervous system, so the cause of all this is obviously an intracranial tumor.

This is a very bad signal.

"What about the urine volume?" Xu Qiu asked.

The nurse gave the answer: 2800 ml.

As if she guessed what Xu Qiu was worried about, she added: "Doctor Xu, Sister Susu reminded us to pay special attention to diabetes insipidus, which is a manifestation of the hypothalamus being compressed and invaded by the tumor.

So the nursing team is very concerned about urine volume.

After checking, the patient's 24-hour urine volume is slightly higher than that of normal people, but it is far from the standard of diabetes insipidus!"

The normal person's daily urine volume is about 1500~2000 ml.

And patients with diabetes insipidus have a daily urine volume of more than 6000 to 8000 ml.

Tao Changhan's urine volume is only 2800, which is more than that of ordinary people, but it is still too little to diagnose diabetes insipidus.

However, he shook his head and judged: "No, the tumor may have affected the hypothalamus."

The little nurse's face changed, and the other doctors in the ward were also stunned.

How did you see this?