Chapter 366: Mystery solved? Was Xu Qiu's diagnosis wrong?

Of course, compared to the new disease, there is another conclusion that is even more unacceptable to everyone.

There was something wrong with the viral PCR, and the detection of a certain virus happened to be missed, which led to conflicting results.

But the possibility of this is also slim.

This examination, like the three-dimensional brain biopsy, was personally supervised and even completed by Xu Qiu, so the chance of errors was very low.

Basically you can ignore it.

At this moment, Joseph, a group of famous doctors, Director Shen, Director Huo and other divine doctors all stopped what they were doing and waited eagerly.

"The problem lies here..."

Xu Qiu touched his empty pocket.

Joseph's expression was startled, and he looked frightened.

Fortunately, Director Huo on the side quickly handed over the red pen, "Doctor Xu, come here."

"Um."

Xu Qiu took over the pen and circled the words "MRZR reaction positive".

Everyone's eyes widened.

What does it mean?

Xu Qiudao: "Next, we can find out the truth by checking the measles virus."

Measles... virus?

This time, not to mention experts such as Joseph and Director Huo, even the attending doctors, residents and interns standing in the corners were full of questions.

How could it be related to the measles virus!

Measles, once one of the most common acute respiratory infectious diseases in children, is very contagious and can cause a pandemic every two to three years.

And there is no magic medicine!

How can a respiratory disease cause a series of central nervous system symptoms?

Not to mention the vastly different systems affected by the two diseases, measles vaccination has been widely available in Daxia for a long time. The vaccination rate among children has been above 99% in recent years, with only a small amount scattered across the country.

In fact, between 2011 and 2012, Daxia almost eliminated measles just as it almost eliminated smallpox.

The WHO is also very excited and is ready to congratulate Daxia for achieving the human goal of "eradicating measles" ahead of schedule.

However, something unexpected happened to both the CDC and the WHO.

In 2010, a large number of anti-vaccination patriots emerged. Countless parents in Daxia believed in the theory that vaccines are harmful, refused to allow their children to be vaccinated against measles, and even forged vaccination certificates to cheat various inspections...

This also stopped Daxia on the eve of eradicating measles. After 2012, measles raged in the country for a period of time, resulting in the death of many children. It was slowly brought under control at a huge cost.

All in all, although one or two cases still pop up from time to time in Daxia, this kind of acute respiratory infectious disease is already considered rare.

When I encountered measles before, the whole hospital was panicked...

Nowadays, many clinicians do not have much experience. Once measles occurs, it is often dealt with immediately by hospital infectious diseases, infectious diseases departments, and superior doctors. Many people only see one or two measles in several years.

At this time, Director Huo suddenly remembered something, "The patient is already old. Has he not been vaccinated against measles in his time?"

Xu Qiu nodded: "The measles vaccine was first used in Daxia in 1965, and the patient was born in 1950, just before the vaccine was widely available."

"No wonder……"

In this way, Fan Fuguo may indeed be infected with the measles virus.

But what does this have to do with diseases of the central nervous system?

Xu Qiu gave the answer again: "There is a rare complication of measles infection, subacute sclerosing panencephalitis.

It is a type of viral encephalitis.

Simply put, the patient may have been infected with the measles virus, or even a mutated strain.

Although the disease improved after subsequent treatment, the immune system failed to completely clear the virus, and a certain degree of immune evasion occurred, resulting in a small amount of virus remaining in the body.

Subsequently, the virus replicates in the body for a long time and gradually spreads to the central nervous system.

Until then, the virus and the body's immune system remain in balance.

However, at a certain moment, the number of viruses finally replicated to a quite large size, breaking the delicate balance between it and the immune system!

This also caused the immune system to attack the nervous system after infection, resulting in an extremely strong immune response and severe nervous system inflammation! "

Subacute sclerosing panencephalitis...

It's like a demon dormant in the body. No one knows its existence, so it quietly recuperates -

When it was powerful enough, it suddenly set off a bloody storm, and finally came to a reckoning with the immune system that had defeated it.

At this moment, the minds of all the doctors in the room were buzzing.

All the mysteries surrounding Fan Fuguo seemed to be solved.

Why are 14-3-3 protein, Tau protein and S-100 protein all positive?

Because the immune system kills infected nerve cells, causing extensive damage to the central nervous system, the three markers rise simultaneously.

Why does it suggest a systemic inflammatory response?

Or the immune system!

The measles virus has been dormant in the patient's body for many years and has spread throughout the body before finally passing through the blood-brain barrier and entering the central nervous system.

At the moment when its fangs were exposed and the balance was broken, the immune system finally noticed it and triggered the entire body's resistance, causing systemic inflammation!

The pathological results and electroencephalogram all suggested viral encephalitis.

However, no viruses that can cause encephalitis were found in the viral PCR, which makes sense.

Before, no one realized that they had to check for measles!

The textbooks have never included measles virus in the records of pathogens of brain disease...

This is no longer a question of whether or not there is clinical experience.

Rather, it is the limitation of the times.

In an era when vaccines are complete and measles patients are scarce, neurologists, respiratory doctors, and pediatricians, no matter how rich their knowledge is, their understanding of measles and measles complications is probably not as good as that of their predecessors before the popularization of measles vaccines in 1965.

...

Soon, the new measles virus antigen test became the last hope.

Before the results came out, the doctors returned to their respective departments and began their daily busy lives.

Xu Qiu also had surgery.

As his status rose, his surgical skills were further recognized. Although Xu Qiu is still only an attending physician, the surgeries he performed were basically level 3 and 4 surgeries that only deputy directors and directors could get involved in.

In addition, the second phase of small blood vessel surgery in Linhai has been carried out simultaneously in five hospitals including Linyi, and is about to come to an end.

At the same time, this epoch-making blood vessel has been shortlisted for the National Technological Invention Award, the Science and Technology Innovation Award, the Science and Technology Progress Award, etc. In the international field, this product has been nominated continuously, and a large number of awards are on the way...

The requirement for being promoted to deputy director is the main personnel of the National Technological Invention Second Prize.

The "attending physician" behind Xu Qiu's title will soon become a thing of the past.

In the afternoon, after two operations, Xu Qiu's hair was messy. He ran to the emergency department to deal with several emergency patients, and finally had some time to rest.

Before the office chair was warm, Joseph, Director Shen and others came to him.

"What's the matter?" Xu Qiu was correcting the medical records submitted by interns and residents, and subconsciously glanced at the red pen in his hand.

He was stunned.

Why is it written on this pen "Linhai International Friendship Hospital"?

Joseph calmed his inner doubts and said: "Xu Qiu, I guessed wrong. The patient's antigen test was negative, and the measles virus was not found at all!"