Chapter 542: Four miscarriages, inevitable tragedy

After scolding, he didn't seem to vent his anger. He glared viciously at the back of his crew-cut relative, and then returned his gaze to Xu Qiu.

At this moment, Flat Nose was no less shocked than his relatives who fled in a hurry.

One phone call was made to the top three deans in the province. The person on the other end was respectful when they heard the name Xu Qiu...

This is not an effect that a god can produce.

When he creates gods, he deceives laymen and the so-called ignorant people.

However, experts often have a clear mind.

However, judging from the current situation, experts praise Xu Qiu even more!

Could it be that the rumors on the Internet are all true and that this young doctor has real abilities?

Boom!

At this moment, Li Xuefeng arrived in a hurry.

Xu Qiu pointed to Yuan Yu and the infant on the hospital bed and asked her to come over for further examination.

Everyone also forgot about the episode just now and focused on the diagnosis and treatment of the disease.

"Dr. Xu, you are right. His development lags behind his age, and there are also slight changes in his skull."

Li Xue was a little worried and said: "The head is larger than that of children of the same age, and the cheekbones are slightly raised. Although they are not very obvious, if you measure carefully, there are still abnormalities."

Xu Qiu nodded and said, "Hereditary liver disease?"

"It cannot be excluded. For young children who are in the rapid physical and psychological development, any systemic disease may have malignant effects on the whole body."

Pediatric disease is a tricky subject.

Unlike adults, they can verbally describe their feelings and changes in their condition, which is often the most important basis for clinicians to diagnose diseases, and various examination items verify their judgment.

Young children can only cry, and doctors can only rely on their own experience to make decisions.

Xu Qiu whispered: "In terms of hereditary liver disease, in the traditional sense, there are only three categories.

“The first is diseases related to large complex molecules; the second is diseases related to acute or progressive poisoning of small molecule compounds; and the last is diseases related to energy metabolism.

"In addition to these, there are also Alagille syndrome, ARC syndrome, Byler disease, etc. In the International Liver Disease Database, there are more than 600 diseases related to liver phenotypes and with clear molecular mechanisms. It is difficult to judge."

Li Xue and others swallowed.

They knew the three major categories well, but the diseases Xu Qiu mentioned that were not included in the classification were also very unfamiliar to them.

Moreover... they even knew clearly that there were more than 600 phenotypes in the database. The next moment Xu Qiu recited these 600 types from beginning to end, just like reciting the names of dishes. They all felt that this was very reasonable.

…

In silence, Xu Qiu rejected the previous speculation of "hepatic glycogen accumulation syndrome".

Although the children have developmental delays,

However, after all-round consideration, the patient did not suffer from the severe hypoglycemia, acidosis, etc. that often occur with this disease when he was born; in addition, there was also no bleeding tendency such as nosebleeds caused by poor platelet function...

There are many causes of short stature and delayed development, and other manifestations are not consistent with the diagnosis of glycogen storage disease and are sufficient to exclude it.

"Hyperbilirubinemia?" Li Xue said.

This belongs to the third category, that is, the liver cells have lost their ability to metabolize bilirubin, causing it to accumulate too much in the body, causing hyperbilirubinemia. It is also a type of familial hereditary metabolic liver disease.

"The child has jaundice, and the bilirubin must be high; there are signs of liver damage elsewhere in the body, and the aminotransferase is probably not optimistic, but it is not hyperbilirubinemia that is the cause, so there is no conclusion yet..." Xu Qiu shook his head.

He turned to Yuan Yu and said, "Have you ever had a premarital examination?"

"Well..." Yuan Yu lowered his head.

Xu Qiu realized that she had misunderstood and said, "Prenatal check-up, a check-up done before giving birth."

"I've done it too..."

Xu Qiu was about to nod when he suddenly realized that the child was born outside of marriage, so he changed the question: "What I mean is, have you and the biological father of the child had premarital and prenatal checkups together?"

Before Yuan Yu could speak, Flat Nose said lightly: "No, this child was an accident. Who would have thought that you could get pregnant during a safe period? I didn't want him at all."

Li Xue's eyes turned cold and said: "There is no such thing as a safe period in medicine. The ovulation period of many women is not completely fixed, especially after having sex, the body's hormones may change. The so-called safe period also has ovulation. Possibility of pregnancy.”

Yuan Yu's head was buried lower on the hospital bed.

In the eyes of her ex-husband, she could be bossy and coquettish, but she never felt confident in front of this man. She always felt that his doctorate degree was too dazzling, and she couldn't hold her head up.

"In other words, I haven't had any prenatal and postnatal check-ups..." Xu Qiu frowned.

If the examination results at that time are available as a reference, it will be much easier to diagnose various genetic diseases.

But now it's very troublesome.

To clearly diagnose this type of disease, the most direct and effective way is to do genetic testing.

However, genetic testing is not just about taking some blood and sending it to the laboratory to find out whether there are genetic defects.

This detection method is more like a carrot pit.

First determine the direction of suspicion. For example, if liver glycogen accumulation type 1 is suspected, then screen the patient's G6*C gene for compound heterozygous pathogenic mutations.

For suspected diagnosis of ornithine carbamate transferase deficiency, check whether the ornithine carbamate transferase gene is abnormal...

Nowadays, Xu Qiu has no knowledge of the biological parents of the child, and it is difficult to screen out suspicious diseases from the lack of characteristic symptoms, so it is not very meaningful to do genetic testing.

"Has this child ever been pregnant before?" Xu Qiu suddenly asked.

He added: "It counts if it was aborted."

Yuan Yu bit her lip and nodded gently.

"How many, why did you abort?"

"Three... because he didn't want it..."

The doctors looked at the flat nose with a hint of disgust and contempt.

Xu Qiu also understood in his heart.

In theory, clinics that dare to carry out artificial abortions generally do not mess around, and it is impossible to cause heavy bleeding under normal circumstances.

Yuan Yu had three miscarriages, and the endometrium was already very weak. If she performed curettage and abortion, the risk factor would soar.

For ordinary people, abortion is equivalent to hanging off the tongue coating on the tongue.

For Yuan Yu, it is similar to scraping off the chewing gum stuck on a balloon.

Let alone small clinics, I am afraid that even the top three or specialized maternity and child hospitals would not dare to do it easily!

"Does anyone else in the family have a genetic disease?" Xu Qiu asked.

Yuan Yu shook her head: "No."

Xu Qiu looked at Flat Nose,

who said impatiently: "No, my family is all highly educated. If there is a genetic disease, I won't have a child, it will pollute the genes."

Xu Qiu came to the bed again and carefully examined the child.

In addition to the series of symptoms caused by liver damage, the enlarged head and raised cheekbones mentioned by Li Xue before are also definite signs, but what do these two items represent?