Chapter 726: Choice of brain nuclei!

Xu Qiu didn't say anything. After thanking him, he and Essette packed up.

Brain pacemaker, also known as dual-channel implantable deep brain electrical stimulation pulse generator, mainly includes several parts, such as generator kit, electrode wire kit and extension wire kit.

These three parts have a lot of technical barriers.

Like the pulse generator of the generator kit, the depth limiter of the electrode wire kit, the electrode tunneling tool, etc.

And the various parts of a single part also require extremely precise control and measurement.

Before the brain pacemaker, studies have long shown that the accumulation of electric charge can cause permanent damage to animal nerve cells.

And this has always been the key reason why various deep brain stimulations are not optimistic.

But Xu Qiu dared to do research in this area because he had found a way to crack it!

As long as a symmetrical bipolar stimulation pulse is used, the total charge obtained by the animal nerve tissue can be zero. In this case, the damage to the nerve tissue can be minimized.

Although there is some damage, compared with the symptoms caused by neurological diseases such as Parkinson's disease, the damage caused by the bipolar stimulation pulse is almost negligible!

Of course, proving that symmetrical bipolar stimulation pulses cause minimal damage is only the beginning.

Traditional bipolar pulses are positive and negative power supplies. The switching speed of the positive and negative poles of the power supply cannot meet the frequency of the positive and negative pulses, but will cause more serious damage to the brain tissue.

And if you want to increase the switching speed, you can only control the switching speed at the nanosecond level through the dual pulse multiplexer designed by Xu Qiu to meet the standards of clinical application.

But...

The core secret of the dual pulse multiplexer is now controlled by Xu Qiu, and other people don’t even know that there is such a core design.

If Xu Qiu didn’t have the god-level scientific research ability, plus the engineering foundation brought by the automatic craniotomy machine, he couldn’t do all this...

Even so, he experimented many times in the simulated operating room before coming up with the final plan.

"There is one last point, the choice of the nucleus location."

In simple terms, it is the area where the brain pacemaker is placed, that is, the place where the electrical stimulation is received.

There are a large number of nuclei in the brain. There are seven large nuclei in the brainstem alone, such as the general trunk motor nuclei, special visceral motor nuclei, etc. There are also several small nuclei under the large nuclei, such as the general somatic motor nuclei including the oculomotor nuclei, trochlear nuclei, abducens nuclei and hypoglossal nuclei...

Which position of the brain pacemaker is chosen is related to the difficulty of the operation on the one hand, and another key point is the body's response to the electrical stimulation of this nucleus position.

To put it bluntly, it is the stimulation effect.

Xu Qiu directly contacted the animal experiment department and asked them to send the twelve SPF-grade male rats they had reserved.

Aise was a little surprised: "Doctor Xu, you don't even take a break?"

"Time is running out."

"SPF male rats? What experiment do you want to do? I'll help you too."

"No, I can do this myself."

Aise paused, picked up a stack of information next to him, flipped through it, and said: "Doctor Xu, are you planning to study brain pacemakers? I see you chose bipolar stimulation pulses, which is a direction that the academic community has not considered before. You are indeed an all-round genius as the rumors say!"

Xu Qiu nodded without comment, thinking in his heart... Can the animal experiment department deliver faster? They are still waiting to open the rats' skulls.

"But I want to remind you that in order to reduce damage to brain tissue, the switching speed of positive and negative poles must be increased, but there is currently no technology that can do this."

Xu Qiu said without hesitation: "It's really not easy to solve."

"Do you plan to increase the switching speed, or use other methods to circumvent it? I'm also studying bipolar pulses, I'll help you!" Aise's voice was excited.

Xu Qiu turned his head and looked at Aise.

This is the person I have the most contact with in the research base. He is honest and a research geek who devotes himself to the project.

In four months, other researchers were unwilling to work overtime, but Essette followed me and worked more than fourteen hours a day, like a desperate man.

Should I continue to study with him as before?

If he stays, the multi-way switch of bipolar pulses may leak!

Just when Xu Qiu was hesitating, Essette suddenly held Xu Qiu's hand and said in a pleading tone: "As a friend, I really want to help you overcome this difficulty! If there is a breakthrough, I may be promoted to professor this year!"

Xu Qiu was stunned.

Compared with other researchers, Essette has no background, so although he is capable and has served as the chief engineer many times, his title is still stuck at associate professor.

He was silent for a moment and asked: "Do you want to participate in this project just to be promoted to professor?"

Essette smiled and said: "Of course not, I want to overcome the difficulties of brain pacemakers and let more patients get treatment! This will be a blessing for patients around the world!"

Xu Qiu also laughed.

He shook his head and said, "Forget it. I only plan to do the experiment on SPF-grade male rats. As for the problem of switching speed, I haven't considered it yet. There are still two months, and I still have time."

Aisette wanted to say something, but when he saw Xu Qiu had turned around to read the progress reports of each group, he was stuck in his throat.

A few hours later, when Xu Qiu went into the animal laboratory alone and closed the door, Aisette punched the table and left the laboratory building with an angry face.

"Dean, it failed."

Esset dialed Dean Miaoyou's phone number.

He lowered his voice and said, "I don't know why, but Xu Qiu seems to be doubting me."

They prepared this plan for four months.

Other researchers were very indifferent to Xu Qiu. Except for work, they regarded Xu Qiu as a transparent person. On the contrary, Essette acted as if she admired Xu Qiu extremely, and was simple but enthusiastic...

In the beginning, he did gain Xu Qiu's friendship.

But I didn't expect that everything was an illusion. Xu Qiu didn't regard him as one of his own!

"He said he hasn't thought of a solution yet?"

Dean Miaoyou thought for a moment and said: "You should continue to hibernate. He is right. There are still two months and this project will not end so soon."

"Okay, but I suggest you give him more stumbling blocks, and I will step in to smooth things over. This way we can get to know Xu Qiu more quickly!"

"This is too deliberate. If the purpose is too strong, there will be more flaws."

"Yes, then I will continue to contact him according to my previous personality."

After hanging up the phone, Essette looked back at the towering No. 3 Scientific Research Building. He squinted his eyes and his pupils suddenly contracted the next moment.

Outside the animal laboratory on the seventh floor, Xu Qiu was leaning on the balcony railing, looking in his direction, with a faint smile on his face...

——

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