Chapter 733 Innovative technology for organ transplantation!
Therefore, those who dare to choose drugs as scientific research results either have great confidence in their own products or are too arrogant.
Selena is clearly the former.
She slowly introduced:
"Migraine is not a simple headache, but a neurological disease that may cause a variety of symptoms. So far, academic circles have not been able to confirm the exact cause of migraine. Migraine treatment drugs on the market also target the symptom of pain. It's a treatment, but more like a painkiller.
"Erenumab refers directly to the chemicals in the brain that affect nerve signals and abnormal brain activity! One of its mechanisms is the use of monoclonal antibody treatment. The internal antibody can be used to block the receptor of the protein CGRP, thereby inhibiting the onset of migraine attacks. Biological cascade reaction, pain-free within two hours after a single oral administration, lasting up to forty-eight hours!”
"..."
Selena's eyes fell on Xu Qiu.
Xu Qiu slightly paid some attention...
This drug is obviously a new drug tailor-made by Novartis Group for the Daxia market.
The experimental data displayed on the screen showed that among the more than a thousand subjects, 80% were from Daxia.
No wonder.
The prevalence of migraine in Daxia is about 9%. There are 130 million clinically diagnosed patients alone, ranking first in the world in terms of the number of migraine patients.
If Erenumab wants to enter the market and achieve profitability, it will never be able to break away from Daxia.
It can even be said that as long as it establishes a firm foothold in Daxia, Erenumab will inevitably become the most important treatment drug in the field of migraine!
"Dr. Xu, she wants to use your help to gain some convenience in opening up the Daxia market." Ambassador Feng Jinpeng reminded in a low voice.
Xu Qiu's status in Daxia's medical community is very high, and this is nothing new.
If Erenumab was developed by Xu Qiu, the country would open a green channel from the beginning of clinical trials of the drug to ensure that there would be no difficulties all the way to the market.
It will be much more difficult for Novartis' new drugs to enter the market. It is highly dependent on Daxia, which in turn means that Daxia has the initiative.
If you can get Xu Qiu's nod, this process will be much easier.
Xu Qiu thought for a while and said: "If the efficacy is clear and the safety is reliable, Daxia will naturally welcome new drugs from global pharmaceutical companies."
Selena in the distance couldn't hear these words, but she still showed a polite smile in the direction of Xu Qiu.
…
Soon, Selena's final results came out.
Innovation scored 89 points, application value 70 points, potential 90 points, and the final score was 83 points.
It is lower than Kenichi Imae, but if you dare to use new drugs as results, you must be prepared to have a very low application value score. Being able to obtain this score is a very rare high score in recent years.
Judging from previous scores, getting into the top ten shouldn’t be a problem!
"It's still a little worse..." Selena was also a little dissatisfied.
She couldn't help but think of Xu Qiu's Seven Stars film.
If the seven-star film is the scientific research result of Xu Qiu World Championship, the score should soar to around 90 points. Not to mention winning the championship, the top three is a sure thing!
"I don't know what his result is, another drug, or something else?" Selina looked forward to it.
…
Soon, the contestants from Berry Kingdom also appeared on the stage.
Lahar had a confident smile on his face. He looked down at the audience and had a strong aura.
All the cameras were focused on Laharl at the same time, and the eyes of countless people around the world were also focused on Berry Country's number one scientific research genius.
"My results may usher in a new era of organ transplantation."
Lahar's first words made everyone stunned.
He then said:
"It is reported that there are 800,000 to 900,000 new liver cancer patients worldwide every year. There are a variety of clinical treatments, some of which rely on targeted drugs such as sorafenib and canavatinib to prolong their lives, and some of which undergo various treatments. It’s similar to chemotherapy, but drug treatment is ultimately the only way to go, and organ transplantation is the most effective treatment!”
These words were very offensive, belittling sorafenib and others, but the target of the words was directly aimed at Xu Qiu’s liver cancer targeting drug Qixing Tablet!
After speaking, Lahar continued to introduce, he said with a smile:
“However, only more than 10,000 people have the opportunity to receive a liver transplant every year. The supply-demand relationship of 1:90 has destined that most people will die while waiting for a liver source.
"Not just livers, but also double lung transplants, heart transplants, kidney transplants, etc., the supply and demand gap for all human organ transplants is huge and growing. We in Berry Country have been exploring new organ transplant solutions...
“And in this World Series, I finally found a glimmer of possibility.
“It’s called – allogeneic cell therapy!
"With this technology, organs can be cultured on human lymph nodes. The successfully cultured mini-organs can perform corresponding functions in the body!"
"..."
An... alternative to organ transplantation?
These words were so shocking that even Xu Qiu raised his head and looked squarely at this so-called allogeneic cell therapy.
All attention was focused on the results displayed by Rahal.
On a giant screen, Rahal showed off the details of the treatment.
Their team had tried to inject cells from healthy livers into the livers of diseased mice in an attempt to treat liver disease, but ultimately failed.
They then tried to inject liver cells into the spleens of mice to replace the function of the diseased liver.
The ending was also a failure.
But in this process, they unexpectedly discovered that liver cells would migrate from the spleen to the liver!
Rahal's team immediately realized that they might have discovered a mechanism that could shock the world.
So they immediately changed their research direction and began to study whether liver cells could migrate from other organs.
In the end, they found the most suitable tissue and organ for migration than the spleen - the lymph node.
This discovery was unexpected but reasonable.
Lymph nodes can provide a suitable growth environment for immune cells and metastatic tumor cells. Among cancer patients, lymph node metastasis is the most common and most troublesome way of spreading, and it has caused countless patients to die.
But in this study, lymph nodes have become a hotbed for the survival, reproduction, growth and development of healthy organ cells!
Subsequent experiments gave them an even more amazing discovery!
The liver cells injected into the mouse lymph nodes can not only survive, but also grow a miniature liver after continuous development. This miniature organ can even play some liver functions!
After that, Rahal's team quickly expanded the experimental subjects from mice to experimental pigs and dogs.
At the same time, they also began to explore more culturable organs, such as the thymus, pancreas, and kidneys.
Rahal also tried the most important transplant organs such as kidneys, lungs, and hearts, but all failed. The only organ that can be used for cultivation is the liver...
