Chapter 808 Rubber Artificial Bone
He stared at the results of PET-CT and bone scans, and said, "Chemotherapy can control her tiny lesions, but the tumor in the patient's left tibia is already uncontrollable. If it is delayed any further, it will be more troublesome to deal with."
The crowd hurriedly looked at the place Xu Qiu mentioned.
Sure enough, the concentration area of the left tibia was shrinking, but some abnormal concentration areas appeared around it.
"Why..."
"Wasn't there any infiltration before, and proximal lesions have begun to appear?"
Everyone's face changed.
The tumor in the tibia is shrinking, but it has not stopped its trend of spreading to the surrounding area.
If the operation is not performed as soon as possible, the leg will definitely not be saved.
At this moment, the problem became extremely clear.
Neoadjuvant chemotherapy is indeed effective, controlling the tiny lesions in various metastatic sites. If the operation is performed a few weeks after chemotherapy, the survival rate will be higher.
However, the distal metastasis is controlled, but the direct spread of the proximal end cannot be curbed...
If we wait any longer, the tibia may not be saved at all, and only extensive resection can be performed.
Either delay it and amputate more safely, with a high probability of saving life.
Or perform surgery immediately to prevent losing the last chance to save the limb, but the risk will be much higher.
"Considering the change in the condition, we have to let the family make a decision again." Xu Qiu thought about it and said.
He sent someone to explain the situation to the family, and the consultation here was not delayed and continued.
"If the patient chooses amputation, just do it directly. The orthopedics department of our hospital is very experienced in this regard."
After Xu Qiu said this, the orthopedic doctor nodded in agreement.
The orthopedics department of Linyi has always been strong. Before Xu Qiu came, hand surgery and orthopedics were the more famous departments of Linyi.
In the past two years, the orthopedics department has been overshadowed by the neurosurgery and emergency departments, but it has also been working hard secretly and is unwilling to fall behind. Therefore, the orthopedics department is also full of talents and surgical elites are frequently produced.
After Xu Qiu finished speaking, he said: "For limb salvage surgery, you have to make a detailed plan."
The difficulty of limb salvage surgery is not comparable to amputation.
Moreover, it involves a key issue - what reconstruction material to use.
Conventional materials must be the inactivated reimplanted bone shell and then filled with bone cement for reinforcement, or the allogeneic bone stored in a low-temperature bone bank for transplantation, but both have significant defects.
The most important point is that bone cement will emit a lot of heat during the solidification process. Under normal circumstances, most tissues in the body can withstand this temperature.
But the problem is that since limb salvage surgery has been chosen, how can the damage to the surrounding bone tissue be light? Therefore, the solidification of bone cement often causes damage to surrounding blood vessels, muscles and nerves.
Especially nerve damage, once it occurs, it is almost irreversible.
This is also the sequelae of many patients who choose bone cement surgery: abnormal sensory nerves in the area of reconstructed bones.
As for allogeneic bone transplants stored in low-temperature bone banks... let alone whether there is a suitable one, rejection is an unavoidable difficulty.
The greatest disadvantage is that it is very easy to have rejection, and once it occurs, the opportunity to save the limb will be completely lost.
"This patient... should be able to use rubber artificial bone?"
While thinking about it, Xu Qiu suddenly had an idea.
At the World Championship, he once developed Guo rubber artificial bone.
This material once amazed the judges of the World Championship and experts in the field of orthopedics at home and abroad.
Traditional bone repair defects have always had huge defects and lack of materials!
What can be used is nothing more than autologous bone, artificial bone, and allogeneic bone.
Autologous bone is a rip-off of Peter to pay Paul, with too many restrictions; the defects of allogeneic bone are too obvious, the incidence of rejection is very high, and the consequences are serious; only artificial bone can be used.
But it is difficult for artificial bone to achieve a balance between plasticity, resistance to liquid phase collapse, and degradation and regeneration.
For example, the main consideration of bone cement has good plasticity and resistance to liquid phase collapse, but it cannot be degraded and has a series of problems such as heat dissipation.
When there is no better material, bone cement is indeed the best choice for most patients with bone defects.
But for Xu Qiu, he still has a killer weapon, rubber artificial bone!
As its name suggests, rubber artificial bone can be shaped at will, and has excellent filling effect. It also has excellent resistance to liquid phase collapse, can be operated stably in various aqueous environments, and can complete bone regeneration in just three to six months after implantation!
It almost surpasses bone cement in all aspects.
Of course, after returning, he handed over the rubber artificial bone project to Lin Xie - the other party is a veteran bone reconstruction expert, second to none in the country, and it should not be too difficult to transform Xu Qiu's results into clinical applications.
Now is the right time to accept the results.
He quickly called Lin Xie.
After a while of greetings, Xu Qiu explained his purpose.
Lin Xie said ecstatically: "Now we have applied ultra-dispersion technology to the industrial chain. I estimate that mass production will be achieved in a few months, and the quality will not be much different from the products from the laboratory!
"Moreover, during this period, we have further improved the sustained release of calcium ions during the degradation of hydroxyapatite, and patients will have a better internal environment during osteogenesis!
"We are going to recruit volunteers in two weeks... It's better to do it today than tomorrow!"
Xu Qiu hung up the phone.
Next, it depends on whether Jiang Dong'er is willing.
If you insist on limb salvage, you can ask about your willingness to use rubber artificial bone.
…
An hour later, the consultation was over, and the surgical plan was finally made at the meeting.
As soon as Xu Qiu left the meeting room, he rushed to the conversation room without stopping.
Jiang Dong'er and Jiang's parents had been waiting for more than ten minutes.
"Sorry for the long wait." Xu Qiu pushed the door open.
Jiang Dong'er's parents immediately stood up, and Jiang Dong'er, who was unable to move, also looked up, and her beautiful eyes lit up instantly.
"Have you decided, limb-saving surgery or amputation?" Xu Qiu said straight to the point.
Choosing amputation will make the hospital quite relaxed, and the patient will also get a safer treatment effect, but the price is losing a leg.
The risk of limb-saving surgery is much higher.
Jiang Dong'er's parents did not speak, but looked at Jiang Dong'er together.
The three of them had already discussed it... Xu Qiu saw the subtext of this action.
Sure enough, after a slight silence, Jiang Dong'er said firmly: "Doctor Xu, I will do limb-saving surgery."
"As expected." Xu Qiu nodded.
Jiang Donger had great trust in him, and he was indeed very confident that he could do this operation...
Xu Qiu sat down as he spoke, and handed over a document, which was a document faxed by Lin Xiecai, which was an introduction to the rubber artificial bone.
"This is..." Jiang Donger's parents were surprised.
Xu Qiu explained: "Traditional bone defect repair surgery mostly uses bone cement, but this reconstruction material has obvious advantages and disadvantages...
"But China is developing a brand-new bone defect reconstruction and repair material, which is the rubber artificial bone you see in your hands."
Hearing the last five words, Jiang Donger's expression suddenly became vivid. She widened her eyes and said in surprise: "I know, I know, it is the scientific research achievement that scored 96 points in the world competition, right!"
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