Chapter 988 The only drug approved in the world!

If you want to get points, you probably have to lock in the type of parasite, and even if it doesn't work, you have to have a general direction.

But there are so many parasites that can cause diarrhea. How did Shi Lian confirm that it was Cryptosporidium?

Shi Lian gave an irrefutable reason: “After Teacher Xu performed a combined heart, liver, and lung transplant, I reviewed a large amount of literature related to organ transplant surgery.

Among them, the most mentioned parasitic infection is Cryptosporidium.

It is also the most important pathogen that threatens the lives of organ transplant patients.

And there's one thing you've all overlooked.

After the patient stopped taking the immunosuppressant, his immune function had just recovered to a certain extent, and the patient's diarrhea was much lighter than before.

Immunosuppressants were restarted, and explosive watery diarrhea developed.

This drastic change is linked to self-limiting infection.

Besides Cryptosporidium infection, how many other parasites are self-limiting? "

This question immediately stopped everyone.

Common parasites actually require deworming treatment.

For example, Cryptosporidium infection is considered a special case. After infection, diarrhea only occurs a few times. The entire organ is not covered with parasites, and there is no vomiting or visible parasites after excretion. Instead, it heals itself...

That's what Cryptosporidium can do.

At this point, Shi Lian put an end to the rest of the discussion, and the condition was completely confirmed to be Cryptosporidium infection.

At the same time, Shi Lian also gave a specific inspection plan, saying:

“To be intuitive, just look at a colonoscopy. A colonoscopy can directly see the changes in the gastrointestinal mucosa.

For laboratory examination, high-throughput sequencing of blood samples must be selected. If the genetic fragment of the parasite can be found, the diagnosis can be confirmed!

There are also routine stool modified acid-fast stains! "

This is considered a test for Cryptosporidium infection.

Almost pointing the gun at Cryptosporidium.

In fact, Shi Lian's approach was to give it a go.

If it's right, it's basically a perfect score.

But if it weren't for Cryptosporidium, the score for this question might be zero... because all her measures were aimed at Cryptosporidium. If the final answers were different, she wouldn't get any process points.

In contrast, many participating teams have chosen more neutral and universal inspection items.

Such as blood routine, stool routine, etc.

It’s hard to say how many are right, and there’s a high probability that it won’t be directly symptomatic, but it definitely can’t be considered a mistake.

…

"Next, treatment!"

Shi Lian quickly came to the next topic.

She had always been slow and unhurried before, but now she couldn't help but speak faster.

Three minutes basically leaves no time for discussion. A topic must be concluded within a few sentences.

This is considered the limit of squeezing, and diagnosis is based purely on clinical thinking and sense of smell.

"What kind of treatment is used, and what is the detailed treatment plan?" Jiang Mai repeated the question.

He has much more experience than others when it comes to parasitic infections.

Mainly because of its own reasons.

Jiang Mai was born in a rural area. He has been running around the mountains since he was a child, catching frogs and chasing rabbits. He roasted the animals and plants on the mountains and stuffed them into his mouth. He had never eaten or seen anything.

What impressed him most about his childhood was not only peeling the skin off a toad and selling it to the owner of a traditional Chinese medicine store, but also... sticking his butt out, and a fat white Taenia solium tapeworm frantically testing the bottom line outside his anus.

Grandma took Jiang Mai's towel, pinched the Taenia solium tapeworm, and then gently pulled it out.

The taste, Jiang Mai still feels a bit scary when he thinks about it.

The most terrible thing is that the old man is reluctant to throw away the towel. After using it, he washes it and returns it to Jiang Mai to continue to use it as a face towel.

In fact, there is nothing we can do about it.

The body of the insect is too slippery and covered in mucus, so it is impossible to grasp it with bare hands. You can only grasp it with a rough towel.

Because of this, Jiang Mai has been interested in parasites since he was a child.

After starting medicine, although he went to surgery, he took the course "Human Parasites" very seriously. He also spent some time in the infectious disease department and emergency department, and was very experienced in dealing with parasites.

In comparison, others are much inferior.

Like Yang Yuen, she has been pampered since she was a child, and then went to study abroad, and then was chosen by the Cleveland Clinic. It can almost be said that she is the growth path of a proud child.

More like a protagonist than Xu Qiu.

Naturally, she cannot come into contact with parasites.

Shi Lian is pretty much the same.

In other words, contemporary doctors have little experience in dealing with parasites.

Thanks to the advancement of the national health plan, parasites are rarely seen even in rural areas, let alone urban doctors?

Even if we encounter one case, most of them are urbanites who have returned from traveling in livestock areas. For example, when they went on a self-driving trip in Sichuan and Tibet, they drank what seemed to be very clear mountain spring water, and when they came back, their livers were covered with hydatid worms.

Shi Lian also looked at Jiang Mai.

Shi Lian was really not very familiar with parasite treatment.

"Let me think about it...the treatment plan is actually very simple. The one used by the international academic community is azithromycin combined with nitazoxanide." Jiang Mai said.

"Nitazoxanide?" Shi Lian and others looked puzzled.

Everyone is familiar with Azithromycin, it is the most famous specific drug for mycoplasma pneumonia.

But nitazoxanide... this thing is very unfamiliar.

Jiang Mai's expression showed a hint of helplessness, and he smiled bitterly: "It's normal that you don't know about this drug, because it is the only drug in the world that is approved for the treatment of Cryptosporidium infection."

On weekdays, doctors don’t see patients with Cryptosporidium.

Even if someone is infected, they think it is diarrhea. If they give the patient medicine for a few days and the patient gets better, they will think the diarrhea is cured.

This is the trouble with self-limiting diseases. The doctor does not even realize that the diagnosis is wrong, and the patient gets better.

Therefore, there are very few patients who can really record "Cryptosporidium infection".

And doctors who use the drug nitazoxanide are even more scarce.

I have never seen it, so I don't know. This is the most normal thing.

Jiang Mai continued: "But there is a very troublesome thing. Nitazoxanide is not approved in China... If you want to use it, I am afraid that the family members have to find a way themselves."

The so-called way is naturally for the family members to ask someone to send nitazoxanide back from overseas.

Or simply ship the medicine directly by sea.

Although it is an unapproved drug, nitazoxanide itself is not a banned drug. A small amount of dosage for treating only one person is not considered a violation.

Therefore, although it is not sold in Daxia, the drug is fine. If you want to buy it, you can still buy it, but it will cost a lot more money.

Shi Lian continued: "This is not a big problem...what else?"

If it is just because it has not been approved, then it is not a problem, and the problem can be thrown to the family members.

The doctor is only responsible for providing a treatment plan.

At this time, she also realized why the sentence "provide a detailed treatment plan" was added behind the second question.

Because the special medicine itself is difficult to obtain, I am afraid that if it can be killed instantly with azithromycin + nitazoxanide, then it is not worthy of being placed in the last question...