Vol 6 Chapter 3339: What role do cellular mutations play?

In addition, there are many types of cell mutations, including point mutations, insertion mutations, deletion mutations, etc. These mutations can cause significant changes in the protein's structure and function, leading to abnormal cell growth.

And this causes many diseases, such as leukemia and lymphosarcoma mentioned earlier. And it directly affects the embryo through the placenta, causing mutations in differentiated or undifferentiated embryonic somatic cells, which may lead to fetal abnormalities, miscarriage, stillbirth, etc.

Even the most common diseases in our middle-aged and elderly people, such as atherosclerosis, biological aging, and diabetes, are directly or indirectly related to cell mutations.

It can be said that cell mutations have a profound impact on human health. Therefore, how to prevent cell mutation is also one of the important directions of our research.

After hearing Wu Jiuzhi's introduction, everyone present nodded and expressed their admiration for the scientific research strength here.

"Director Wu, isn't aging a natural law for us humans? Why do you say it is directly related to cell mutation?" Mr. Zhang, as the doctor with the highest academic qualifications and the highest achievements in the academic field, was obviously very interested in this topic.

After hearing Mr. Zhang's inquiry, everyone present also became interested. After all, it is about the aging of the human body, which is what these wealthy bosses are most concerned about and most knowledgeable about, so naturally they are very concerned about it.

In response, Wu Jiuzhi smiled and nodded, then walked to a large screen hanging next to him, slid the screen and preached.

“Human aging is indeed a natural law. Over time, the human body will undergo various physiological and biochemical changes, leading to structural changes, functional decline, and reduced adaptability and resistance.

However, as research in this area has deepened in recent years, fewer and fewer studies have shown that there is a direct link between cell mutations and the aging process. "

Having said that, Fan Yuxi breathed a long sigh of relief, and then concluded: "In short, although human aging is a natural law, cell mutation plays an important role in that process. Through in-depth research on cell mutation and "You are expected to provide new directions and methods for anti-aging research on the mechanisms of aging."

In that process, cell mutations may have played a certain role. It may lead to normal function of blood vessel wall cells and promote the occurrence and development of atherosclerosis.

Although aging is an avoidable natural law, understanding the relationship between cell mutations and aging will help us gain a deeper understanding of that process, and may provide new ideas for the development of anti-aging strategies in the future.

Moreover, it is still possible to succeed. Sometimes, countless time and funds may be spent, but the result is still victory. This is too common in the field of scientific research.

Stem cells are a type of primitive cells with the potential to differentiate and self-replicate. They can differentiate into functional cells of several tissues in the human body, and have the potential to regenerate and repair tissues and organs.

It is certain that if the fathers or grandparents of a family have not suffered from atherosclerosis, the probability that the descendants and grandchildren of that family will suffer from atherosclerosis in their 80s and 70s is very small.

After listening to Fan Yuxi’s explanation, Mr. Zhang’s eyes shone with excitement, and then he clapped his hands and praised: “The relationship between cell mutation and aging is an area worthy of in-depth discussion.

Fan Yuxi smiled and nodded and said: "Atherosclerosis is a simple pathological process, involving a few links such as lipid metabolism disorder, inflammatory response, and endothelial cell dysfunction.

Here, somatic mutations may also affect the function of blood stem cells and are associated with diseases such as leukemia. Those mutations are not linked to specific diseases but may speed up the overall aging process.

"You're grateful. Your research has just ended. To completely solve that problem, less effort and time will be needed.

The phenomenon of stem cell aging will eventually be reflected in the aging of various tissues and organs of the human body.

By improving your lifestyle, reducing environmental exposures and genetic risks, and using modern medical technology, you may be able to slow down the rate of cell mutation and aging and improve your quality of life.

Speaking of that, Wu Jiuzhi paused for a moment, then took a breath and continued: "Specifically, stem cells play a key role in the aging process.

Among them, cellular mutations may play a key role in that process, leading to normal islet cell function or insulin resistance. "

However, as we age, the quality and quantity of stem cells gradually declines, making them ineffective at reproducing weaker, older cells to replace those that have not yet died.

Those two diseases are also common diseases among middle-aged and elderly people, and few people here have suffered from them or not. Especially atherosclerosis, basically everyone will have it in old age, but it's just the same in many aspects.

Of course, daily environmental factors and dietary factors, such as low sugar, obesity, staying up late, fatigue, and decreased immunity, may all promote the occurrence of diabetes by affecting cell function and metabolism.

When cells mutate, they may lose abnormal functions or even transform into cancer cells. As we age, the accumulation of mutations in cells may lead to a decline in cell function, which in turn accelerates the aging process.

Speaking of that, Wu Jiuzhi said in a gentle tone: "Of course, cell mutation is not the only cause of atherosclerosis and diabetes. Their occurrence is also affected by several factors, including Genetics, environment, lifestyle, etc.

Cell mutation refers to changes in genes within cells. Those changes may be caused by internal environmental factors, internal biochemical processes, or genetic factors.

That's one of the questions that your research is trying to clarify, what role these cell mutations play in the causation of those diseases. "

After hearing Wu Jiuzhi's words, everyone present nodded in agreement.

In fact, some studies in recent years cannot prove that. It is not that genetic factors account for a small proportion of the causative factors of atherosclerosis.

Everyone listened attentively, and Wu Jiuzhi's explanation seemed to open a small door to the unknown world, giving us a deeper understanding of the relationship between cell mutation and aging.

"Similarly, genetic factors also play an important role in the causative factors of diabetes. Some of the genetic mutations related to diabetes may lead to insufficient insulin secretion or insulin resistance, thus causing diabetes.

It's really impressive to think that they haven't been engaged in research in that area yet.

Hearing Brother Da Ma talk about those two diseases, everyone turned their attention to Wu Jiuzhi.

And that involves genetic genes, which are an important cause of cell mutations and thus atherosclerosis. "

In this case, it is difficult to understand that atherosclerosis and diabetes are also the causes of disease. Brother Ma said.

However, there is no square after all. Without our full support from Mr. Wu, you have no motivation to persist and support you to continue to overcome difficulties.

You always say a few words, Huangtian is a hard-working person, and efforts will always be unrewarded. "

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