Chapter 325 Medical grade protein structure synthesis technology (4/4)

During the Chinese New Year, although he was threatened by his younger brother Ye Zihua that he would tell his parents if he worked so hard, he also agreed and prepared to take a break.

But this year's events are one after another, it is impossible to take a break, so he still basically lives in the company, and rarely returns to the nearby employee's home to rest.

When Pei Qing moved to live next door, she made a special phone call to tell Ye Zishu, but the two of them had passed by for several months, and they hadn't met face to face.

So this time when Pei Qing invited her to have dinner at her house, he really couldn't find a reason to refuse, besides, he felt that it was a pleasure to be invited by such a beautiful woman.

Pei Qing left Ye Zishu's office with a relaxed pace, while Ye Zishu sat down and thought about the vaccine.

Traditional vaccines definitely need to be developed. Although this kind of vaccine will not bring great profits to Taiji Group, it is very important to reduce the health risks of domestic people.

Moreover, the export of these vaccines to the third world is also of strategic significance. As for the developed countries, don't think too much about it. Their own medical technology is not bad, and it is impossible to purchase the traditional vaccine products of Taiji Group.

Therefore, if you want to obtain better income in the field of vaccines, you still have to come up with monopoly products, such as HIV, which was first discovered in Laos in 1981.

Decades later, no vaccine against this virus has been developed. If Taiji Group can come up with this vaccine, it will be able to continue to monopolize the global AIDS vaccine for decades.

Although the proportion of patients with this disease is not high, it is difficult to treat and it is very troublesome. If you can get this vaccine at an acceptable price, most people are still willing.

There are also HPV vaccines for women's health. There are hundreds of types of HPV isolated, of which as many as 14 can cause cervical cancer or other tumors.

It is very likely that there will be other undiscovered HPVs that cause other symptoms, which makes the development of HPV vaccines particularly difficult.

The bivalent HPV vaccine we often say can only prevent two types of HPV, and the following four-valent and nine-valent HPV vaccines are the same, but the number of HPVs protected is limited.

Therefore, in the field of HPV vaccine research and development, technology leadership has an absolute advantage, has great research value, and also fills the gap of such high-end vaccines in China.

Ye Zishu lists the list of vaccines that need to be developed on the computer file. There are more than 30 types, some of which are already available products, and some are original products of Taiji Group.

After listing,

Ye Shu thinks about how to achieve this. If traditional inactivation methods are used, it is difficult to produce complex vaccine products, because it is impossible to fuse multiple subvirus types together.

For example, the above-mentioned HPV virus has too many types, and traditional methods can only be used to make vaccines for limited HPV viruses, and cannot achieve comprehensive defense.

There is also the HIV virus, a virus that can bypass the immune system and even destroy the immune system. It is not easy to make a vaccine against it.

The most important thing is that if we only come up with a targeted plan for each virus, it will be difficult to keep up with the situation that there will be more and more viruses in the future, which will cause more and more harm to the human body.

Although the living conditions of human beings are getting better and better, it seems that the stronger the ability to resist diseases, in fact, this is the relationship between spear and shield. With the improvement of human medical level, the evolution rate of viruses is much faster than before.

In just a few hundred years since humans entered the industrial age, more types of viruses have emerged than in ancient times, and the speed may be further accelerated in the future.

Therefore, in order to deal with viral diseases that will appear in the future, Tai Chi Group needs a set of advanced medical technologies and concepts that can come up with solutions faster than traditional production methods.

Therefore, what he needs to come up with is not the traditional inactivated vaccine production technology, nor the relatively advanced mRNA production technology in his previous life, but the technology that belongs exclusively to his company.

That is the protein synthesis technology. Originally, this technology will be used in various protein production fields of Kirin Industrial Group, such as milk, which is to synthesize the target protein step by step from the simplest carbon, hydrogen, oxygen and nitrogen.

In fact, the pathogenesis of the virus is also caused by the protein shell and spikes, and the internal RNA or DNA only plays the role of virus replication.

Vaccines imitate the pathogenic mechanism of viruses, allowing the human immune system to generate immune cells and proteins in advance without damaging human health, forming immune memory.

Therefore, as long as the target vaccine is directly synthesized through protein synthesis technology, the safety is the highest among all vaccines, because it can be guaranteed not to contain any DNA or RNA.

In addition, this synthesis technology can easily control the production of target proteins, and can develop multivalent vaccines that integrate the characteristics of various related viruses, which plays an important role.

Like the HPV vaccine mentioned above, the nine-price vaccine is already considered good, and the price is more than 1,000 yuan per injection. Before the rebirth of Ye Zishu, there was no 14-valent vaccine in China.

However, as mentioned above, there are more than 100 types of HPV viruses. Even the 14-valent HPV vaccine cannot achieve comprehensive defense. It can only defend against HPV that can cause serious diseases.

Although the basic principles of the protein synthesis technology used by Kirin Industrial Group are similar, one is used for medical treatment and the other is used for daily life, and there are still big differences.

In terms of the level of technology, it must be that medical-grade technology has higher requirements. Ye Zishu needs to come up with higher technology starting from the stage of protein synthesis from amino acids.

As for the technology of synthesizing amino acids from simple elements, the two can be completely shared. Although Kirin Industrial Group produces daily products, the purity of all kinds of amino acids synthesized must reach medical grade.

In addition to this heavyweight technology, in order to speed up the Taiji Group's research on various vaccines, he needs to provide detailed case analysis and development ideas for each vaccine and the virus it fights.

However, even with the provision of these materials, Taiji Group still needs to establish its own virus laboratory. Any experiment related to viruses needs to be treated with caution, and it must be foolproof.

However, in the early stage, for viruses that are not particularly serious, you can borrow the National Virus Laboratory to do related experiments, and you don't need to wait until your own laboratory is completed.

At present, they will not conduct particularly high-risk virus research, and only need a P3-level laboratory. In 1987, my country built a P3 laboratory for the study of HIV.

Taiji Group can completely borrow this laboratory to complete some experimental research, and can even spend money to purchase existing research results from national research institutions during the research on AIDS vaccines.

As for the cost, in fact, the cost of using protein synthesis vaccine technology is higher than that of ordinary inactivation technology, but as long as the output is high enough, the cost reduction is very fast, and it is very competitive.

However, the supply of raw materials for Taiji Group can be carried out by Kirin Industrial Group, so there is no need for a series of investment in pre-links, which saves a lot of investment costs.

The Kirin Industrial Group itself needs a huge amount of amino acid products to synthesize proteins, and the large output will lead to very low costs.

Therefore, the combination of the two, the cost of vaccines produced using protein synthesis technology is much lower than that of ordinary vaccine production technologies, which has a strong competitive advantage.

While collecting information, Ye Zishu was conducting related experiments in the laboratory. He was very cautious about the medical-grade protein synthesis technology, and he had to be sure that nothing would go wrong.

He will take it out and write it into the technical information when the experiment in the virtual laboratory is passed and the technology is not particularly demanding in reality.

So things that seem to be very simple feel much simpler than the business involved in Kirin Industrial Group, but it also takes a lot of time. He plans to take half a month to sort out these materials.

The time quietly came to 6:30 in the evening. Ye Zishu looked at the time, saved and encrypted the data, turned off the computer, and then began to put on his coat to prepare for the appointment.