Vol 2 Chapter 1911: Advanced "meaty" preservation technology

Genius to remember the address of this site in one second: []The fastest update! No ads! "We have developed a special cultivation equipment, in which the relevant nutrient solutions needed for cell growth are injected into the equipment, and a simulated in vivo environment suitable for cell growth is created, such as temperature, value, sterility, and even light, etc. .

Then, we will extract the corresponding cell precursors from the patient. It does not need too much, just a little bit, and it will not cause harm to the human body.

Of course, the extracted cells must meet the relevant requirements, and if they do not meet the requirements, they must be re-extracted. Even sometimes the cells in the patient may not be used, such as long-term drug reuse, radiotherapy, chemotherapy, etc., which will affect the patient's own cells and make them unable to meet the extraction standards. Then, at this time, we only Relevant cells can be extracted from the patient's parents or children, thereby reducing the patient's body's rejection of the printed organ tissue.

The extracted cells cannot be used directly, but need to be pre-treated to maintain the viability of these cells, and to reveal which unqualified cells and other impurities are included.

After completing such a series of steps, the next step is to put these cells into the cultivation equipment for relevant cloning culture. And add appropriate hormones in this culture process, so as to accelerate the whole process of cell division and growth.

Don't be biased against hormones. In fact, our human body is inseparable from the stimulation of various hormones. Even the division and growth of cells cannot be separated from hormones. Of course, this must be controlled within a reasonable range, too little or too much will affect cell division and growth.

Through this technical method, we can obtain a large number of cells. Generally, within 24 hours to 36 hours, the printing conditions can be met, and then these cloned and cultivated somatic cells will be transferred to the bioprinter. to print in.

During the entire printing process, a steady stream of freshly cultivated cells in the cultivation equipment will be transported over, directly supplied to the bioprinter, and used in printing to ensure that the printed organs and tissues are sufficiently fresh and vibrant. "

Speaking of this, Wu Hao slightly softened his tone, and then continued: "Everyone knows that the printing speed of this stacked printer is very slow, and the same is true for this bioprinter. It uses cells with a few micrometers to print a huge Organs, taking the smaller organs such as the heart and kidneys that we are most familiar with, will take at least several weeks to print out of cell stacks.

Such a printing speed is too low to be applicable at all. It should be known that the optimal transplant time for human organs after ex vivo is within hours, and even some organs have already caused irreparable losses within a few hours.

This is still pre-processed, and if it's not, then it's just a piece of dead meat, and it's useless at all. It even stinks over time.

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The same is true for bioprinted organs. How to keep the printed organs and tissues active for a long time is also a problem considered by our scientific research and technical experts. Because printing takes too much time, if the printed organ tissue cannot be guaranteed to remain active, then the organ tissue has not been printed, and the part that started printing first is broken.

Therefore, we must increase the entire printing speed and control the printing time of the entire organ within a short period. However, if the printing speed increases, the printing accuracy will decrease accordingly.

This seems to be an irreducible contradiction, but after careful analysis, it is nothing more than a higher and more demanding requirement for the overall performance of the bioprinter. "

"So, we first need to increase the printing speed of the bioprinter while ensuring the printing accuracy and printing quality. It is very difficult to speed up this kind of bioprinting, because what we use is cells and what we print is organ tissue.

As a result, this creates constraints and many unexpected problems.

For example, if the printing speed is increased, the printing needle is prone to be blocked by the rapidly inflowing cells, resulting in failure. Secondly, the flow rate in the cell supply system is too fast, which will also cause damage to the cells to be printed and so on.

So this is not only as simple as speed regulation, but also involves a lot of problems, which can be said to affect the whole body. "

"Secondly, it is necessary to solve the problem of preserving the freshness of the printed organ tissue. No matter how fast it is, it will reach a technical limit, so the preservation of the organ tissue that has been printed in this printing room is also an urgent problem to be solved.

Conventional organ preservation techniques include cryopreservation and perfusion of immersion preservation solutions, but generally these two methods work together. But even so, it still can't be extended for much time.

Therefore, it is necessary to have more advanced biological preservation technology to maintain the biological organ tissue vitality of these printed organs during the printing process.

In order to solve this problem, we finally solved this problem after numerous exploration experiments. Our expert technical team plans to install a biological organ printing chamber under the bioprinter. This printing chamber can be regarded as a biological organ printing room, or can be regarded as an artificial organ hotbed, or an organ placenta.

This printing chamber is generally injected with a special preservation solution during the printing process, or injected with some specially protected inert gas. The entire printing process is printed in these preservation liquids and inert gases.

This method greatly isolates bacteria in the air, so that the entire printed organ tissue is kept in a sterile environment, which greatly prolongs the activity of the printed organ tissue part.

The combination of inert gas or preservation solution and low temperature environment can greatly prolong the active time of the whole organ. As a result, even the biological organ tissue part that has been bioprinted for a long time can maintain its biological vitality and be in the best transplant state. "

"Of course, we are still researching this bioprinting technology, and there are still many technical problems that have not been solved. So its capabilities are very limited.

Today, what we show you, in addition to this bioprinting technology, as well as the corresponding bioprinters, and cell clone cultivation equipment.

And the related achievements we have created using this technology, remember the short film we just started? "

Wu Hao raised this question with a smile. Hearing Wu Hao's words, everyone watching the live broadcast suddenly remembered the content of the previous short film and the introduction of Wu Hao at the beginning.

Wu Hao, who paused for a while, smiled at this time: "Yes, we have successfully printed artificial skin tissue using this bioprinting technology!"